Twenty five studies tested for dengue and of those, nine (36%) did not specify type of testing done for diagnosis while 16 (64%) studies documented the use of specific tests like dengue immunoglobulin M and/or G enzyme linked immunosorbent assay or immunochromatographic test (IgM, IgG, ELISA, ICT) and Non-structural protein 1 antigen (NS1) (ELISA or ICT) (Fig. 4b) [2, 16, 48, 50, 55, 56, 58, 62, 64, 70, 72, 77, 78, 80, 82, 85]. This evidence concerns the gene CD40LG and dengue disease.