DDIT3 and sarcoma: Unlike WD/DDLPS, MLPS is a translocation driven sarcoma and is characterised by the recurrent translocations t(12,16)(q13;p11), and less commonly t(12,22)(q13;q12), which fuse FUS RNA binding protein (FUS) or EWS binding protein-1 (EWSR1), respectively, to DNA damage inducible transcript-3 (DDIT3) on chromosome 12.