While monocyte proportions were not available, we observed that both XY- and autosomal-iSEXS scores were positively correlated with CD4+ T cell percentages in female patients with SLE (XY-iSEXS: r = 0.6, p = 5.52e-5; autosomal-iSEXS: r = 0.35, p = 0.03; Figures S6G and S6H). Here, CD4 is linked to systemic lupus erythematosus.