CEACAM5 and colorectal carcinoma: Yamamoto et al.27 reported that the 5-year OS and DFS of patients with higher CEA (carcinoembryonic antigen) mRNA expression levels, top 30% of micrometastases in pStage II CRC, were significantly low, and the volume of micrometastases was related to the prognosis of the pStage II CRC.