CD4 and cancer: CD4+CD25+ FOXP3+Helios+, CD4+CD25-FOXP3+Helios+and CD25+FOXP3+CD73+CD39+Tregs wereexpanded after co-culturing of T cells with both cancer-ASCs and normal-ASCs, while they were statistically significantonly in the presence of cancer-ASCs (P<0.05).