The results revealed that co-culturing of naïve Tcells with ASCs increased CD73+CD39+, but not CD73-CD39+ and CD73+CD39- subsets of T cells, which wasstatistically significant in the presence of cancer-ASCs.Interestingly, CD25- FOXP3+CD73+CD39+ cells werereduced after exposing to both cancer- and normal-ASCscompared to the control group. Here, ENTPD1 is linked to cancer.