CDKN2B and gestational diabetes: Our results demonstrated that hypomethylation of CpG sites in the vicinity of CDKN2A and CDKN2B genesis positively related to increased levels of CDKN2A/B mRNA and protein in islets of Langerhans in the GDM offspring.The average percentage of CDKN2A promoter methylation was significantly lower in GDM group compared to thecontrols (P<0.01).