Although the precise etiology of MS is still unrevealed, multiple genetic pathways have beenidentified to participate in the pathogenesis of MS, including HLA- DQB1*0602, HLA-DQA1*0102,HLA-DRB1*1501,and HLA-DRB5*0101 (3), as well as some microRNAs namely, miR-326 and miR-26a (4). The gene discussed is HLA-DRB5; the disease is myeloid sarcoma.