The incidence of GDM was remarkably reduced and found to be only 6% in the group treated with myo-Ins when compared to the placebo group, which had a GDM-incidence rate of 71% [10]. Moreover, the group treated with myo-Ins showed remarkable improvement in terms of secondary outcomes as well: they required less insulin therapy, showed reduced incidents of premature births, and delivered significantly smaller babies with fewer instances of neonatal hypoglycemia [10]. This evidence concerns the gene INS and gestational diabetes.