However, uptake by macrophages seems to be a common mode of elimination of PVA MBs of various types, even those not coated with antibodies.2,29 The fact that macrophages from animals with peritonitis seemed to have a higher affinity for/uptake of anti-ICAM-1-MBs compared with control MBs in flow cytometry experiments indicated an effect of the antibodies. This evidence concerns the gene ICAM1 and peritonitis.