HSP90B1 and neuroblastoma: Wogonin activates mitochondrial and ER stress-related pathways including the modulation of Bcl-2 family proteins, cytochrome c release, GRP78 and 94-kDa glucose-regulated protein (GRP94) accumulation, and caspase activation in human neuroblastoma SK-N-BE2 and IMR-32 cells, and induces mitochondrial dysfunction through IRE1α-dependent pathway [704].