In addition, wogonin also represses multiple myeloma-stimulated angiogenesis through c-Myc/von Hippel-Lindau tumor suppressor (VHL)/HIF-1α signaling pathway [725], LPS- and H2O2-induced angiogenesis through PI3K/Akt/NF-κB pathway [726, 727]. The gene discussed is VHL; the disease is AL amyloidosis.