CDKN2B and malignant glioma: As a CNV-driven ceRNA, CDKN2B has been reported to serve as a functional unit in the oncogenesis of malignant gliomas (Shete et al., 2009; Weller et al., 2009), its ceRNA pairs, CDK2 and RBL1, were also annotated in cell cycle and located in the downstream of the pathway (Figure 4C).