TRIM27 and esophageal squamous cell carcinoma: To further examine the function of TRIM27 in ESCC cells, we synthesized three short interference RNAs (siRNAs) targeting human TRIM27 (siTRIM27-1, siTRIM27-2 and siTRIM27-3) and a nonspecific scrambled siRNA (siNC) and subsequently transfected into KYSE150 and TR-11 cells.