AKT1 and Burkitt lymphoma: Although PTEN mutations are rare in BL in comparison with GCB-DLBCLs [11, 25, 56, 57] and its expression can be identified by immunohistochemistry in most BL samples [58], it was suggested that miR-17-92HG-dependent PTEN repression activates PI3K-AKT in BL.