Several of the mapped genes of these lead SNPs have previously been identified with multiple other traits, such as body mass index (FHIT, KLH31, ADAMTS17, and MAGI2), mental health (FHIT [autism/schizophrenia, depression], SNX13 [cognition]), gamma-glutamyltransferase (ZNF827, MICAL3), and inflammatory processes (ZNF827, NR5A2). This evidence concerns the gene NR5A2 and major depressive disorder.