TBC1D2B and non-small cell lung carcinoma: Preliminary experiments transiently overexpressing each of the three hits yielded from the analysis of the ENCODE ChIP-seq data (Supplementary Fig. 6a, b) suggested that all three genes significantly affect in vitro migration and invasive potential of murine NSCLC (Supplementary Fig. 6c); however, TBC1D2b posed an intriguing candidate.