In our patient cohort, high numbers of CD8+ TILs were observed in patients with PD-L1high NSCLC (p < 0.05, data not shown), whereas the number of CD8+ TILs tended to be inversely correlated with HK2 expression in PD-L1positive NSCLCs. The gene discussed is HK2; the disease is non-small cell lung carcinoma.