Since chemokine receptors are key downstream effectors of angiogenesis induction, we evaluated the regulation of CXCR4, CXCR1, CXCR2, CCR2 expression on endothelial cells, incubated with conditioned medium from ALCAR treated PCa and BPH cell lines. This evidence concerns the gene CXCR2 and benign prostatic hyperplasia.