The AUC of IL-6 to discriminate sepsis from the control group was 0.89 (95% confidence interval [CI], 0.97–1.00; P < 0.001), 0.84 for PTX3 (95% CI, 0.95–0.99; P < 0.001), 0.80 for PCT (95% CI, 0.86–0.96; P < 0.001), and 0.77 for CRP (95% CI, 0.71–0.91; P < 0.001) (Table 2 and Fig. 3). The gene discussed is PTX3; the disease is Sepsis.