RB1 and Insulin resistance: To examine the effect of RB protein hydrolysates on insulin resistance, Boonloh, Kukongviriyapan [19] utilised HepG2 cells in which insulin resistance was induced with either IL-6 or high glucose, and the regulation of insulin signalling was examined after treatment with different concentrations of RB protein hydrolysates (400–1600 μg mL−1).