Likewise, immunohistochemistry of specific molecular markers of the tumor CRCs cultures showed that the normal CRC cells stained negatively to the proliferation marker Ki-67 (33) (Figure 2) and moderately positive P63 (Figure 2) a well-recognized differentiation marker [72], while the malignant cells stained moderately positive to Ki-67 (Figure 4) as well as P63 (Figure 2). The gene discussed is MKI67; the disease is colorectal carcinoma.