Follicular Lymphoma, for example, ubiquitously expresses BCL-2 owing to the t(14;18) translocation which juxtaposes BCL-2 to the immunoglobulin heavy chain promotor; however, modest overall responses of 38% were observed in this disease in the Phase 1, first in human, trial of venetoclax [94]. The gene discussed is BCL2; the disease is follicular lymphoma.