The incidence of endophthalmitis has also steadily risen over the past two decades due to the increased popularity of suture-less cataract surgery, small-gauge vitrectomy, and intravitreal injections of anti-vascular endothelial growth factor (VEGF) drugs for treating age-related macular degeneration and diabetic macular edema [4,5]. This evidence concerns the gene VEGFA and diabetic macular edema.