CRP and Increased total leukocyte count: Univariate Cox proportional analyses identified leukocytosis (p < 0.001), neutrophilia (p < 0.001), monocytosis (p < 0,001), elevated NLR (p < 0.001), elevated LMR (p < 0,009), elevated CRP (p < 0.001), and elevated tumor marker CEA (p < 0.019) as significantly associated with shorter OS (see Table 2 for further details).