Patients receiving only 1st line palliative chemotherapy had statistically significantly higher inflammation markers including elevated CRP (p < 0.004), leukocytosis (p < 0.001), neutrophilia (p < 0.002), and elevated NLR (p < 0.011) compared to patients receiving a 2nd and 3rd line therapy according to Pearson ́s chi-squared testing. The gene discussed is CRP; the disease is Increased total leukocyte count.