AXIN2 and neoplasm: The lncRNA-PLIN2 also upregulated in CML patients by a CEBPA induced-mechanism, increased in turn the expression of AKT, p-AKT, GSK-3β, β-catenin and Axin2/conductin, and could promote tumor growth by activating GSK3 and Wnt/β-catenin signaling in-vivo [119].