CSF2 and neoplasm: Most importantly, immunohistochemistry with a CD3 antibody showed very few CD3-positive (CD3+) T cells infiltrating the tumor mass in control mice; noticeable, but still low CD3+ T-cell infiltration in GM-CSF/AWE-treated mice; sections from proTα/AWE- and especially proTα(100–109)/AWE-treated animals were enriched in CD3+ tumor-infiltrating T cells (Figure 3E).