However, an extensive earlier study by Trojanwski and colleagues failed to find evidence for the transmission of disease in such growth hormone recipients based on inoculation of proteins associated with Alzheimer’s disease, frontotemporal lobar degeneration-tau, or Parkinson’s disease (i.e., amyloid-β, tau, or α-synuclein) [90]. This evidence concerns the gene GH1 and frontotemporal dementia.