FADS2 and metabolic dysfunction-associated steatohepatitis: LPL gene encoding for lipoprotein lipase was the most over-expressed gene in NASH with a fold change of +1.93, followed by chemokine CCL2 (fold change = +1.61) and the enzyme FADS2 (fatty acid desaturase 2, fold change = +1.57) as summarized in Supplementary Datasets Table S2 online.