PLEK and cancer: These 13 genes include genes involved in regulation of fatty acid and cholesterol metabolism such as LPL, VLDLR, LIPA, ANXA2, and PLEK; lipid accumulation (CIDEC, PLIN1); and metabolism (PPARA and BCL2A1); and especially genes implicated in inflammatory and cancer processes such as CCL2, CD36, TUBA1A, and YWHAZ (Figure 9C).