The cancer pathway is also associated with two genes implicated in the cytoskeletal remodeling and network, ANXA2 and TUBA1A, linked to HCC and cell migration (i.e., metastasis development) as shown previously [66,67], thus predicting the fate of the NASH (Figure 8F). The gene discussed is ANXA2; the disease is metabolic dysfunction-associated steatohepatitis.