Interestingly, this effect of treatment timing on TTNT was not observed in MF/SS patients receiving other systemic therapies: a retrospective study of 88 MF/SS patients treated with a range of systemic therapies found no statistically significant difference in the TTNT of early delivery (lines 1–2) versus later delivery (>2 lines) for interferon, HDAC inhibitors, and chemotherapy [12]. Here, HDAC9 is linked to synovial sarcoma.