STAT3 and T-cell large granular lymphocyte leukemia: Hyperactivated STAT3 is identified in patients with diverse phenotypes and multiple somatic mutations have been associated with T-LGLL (T-cell large granular lymphocytic leukemia, 40–70% of all cases) and NK-LGLL (natural killer cell large granular lymphocytic leukemia, 30% of all cases), as well as different hepatocellular adenomas [40].