In mucoepidermoid carcinoma of the lung, HMOX1 overexpression was also associated with the inhibition of cell-cycle progression proteins Cyclin D1 (CCND1) and CCND2, and the stimulated transcription of the cell-cycle arrest proteins Gastrin (GAS) and Cyclin-dependent kinase inhibitor 1C (CDKN1C). This evidence concerns the gene CDKN1C and pulmonary mucoepidermoid carcinoma.