The lncRNA SNHG16 functions as an oncogene in multiple cancers and acts as sponge for many miRNAs (such as miR-98, miR-216-5p, miR-302a-3p, miR-497, miR-140-5p, miR-1301, miR-218-5p, miR-195, and miR-135a), thereby regulating expression of genes involved in multiple human cancers (Figure 6B), such as breast cancer [72], cervical cancer [73], HCC [74,75], papillary thyroid cancer [76], retinoblastoma [77], bladder cancer [78], osteosarcoma [79], pancreatic cancer [80], and gastric cancer [81]. The gene discussed is SNHG16; the disease is cancer.