However, 57.1% (32/56) of GAS5-mediated regulations are disease-specific, as illustrated by the finding that GAS5 regulates cell proliferation, cell migration, and cell invasion by sponging miR-18a-5p in glioma (32) but sponging miR-196a-5p in triple-receptor negative breast cancer (33). This evidence concerns the gene GAS5 and central nervous system cancer.