For example, integrin α7 interacts with S100P to promote cells migration and cells invasion in lung carcinoma.10 Another mechanistic study discloses that integrin α7 induces cells migration and invasion abilities via the activation of epithelial–mesenchymal transition (EMT) in OSCC.6 In addition, parts of previous studies have revealed that integrin α7 possesses effect on regulating stemness of cancer cells. The gene discussed is S100P; the disease is cancer.