In HNSCC samples with metastasis, the expression of miR-211 is negatively correlated with expression of TGFβR2 protein, and in consequence is associated with poor prognosis for HNSCC patients (Chu et al. 2013). Zheng et al. (2018) also reported overexpression of miR-211 in tissues and cell lines from oral cancer, and interestingly found that higher miRNA expression is correlated with decreased expression of the tumor suppressor gene BIN1 (bridging integrator-1) which may be a target of miR-211. This evidence concerns the gene TGFBR2 and head and neck squamous cell carcinoma.