TIMP2 and acute kidney injury: We performed an ROC curve to evaluate the predictive ability of [TIMP-2]∙[IGFBP7] for AKI: patients with AKI within 12 hours (AUC 0.74 (95%CI 0.69–0.80)), 48 hours (AUC 0.70 (95%CI 0.65–0.76)) and between 48 hours and 7 days (AUC 0.40 (95%CI (95%CI 0.28–0.52)) (Figs 1 and 2; Supplementary Table 2S).