As far as the [TIMP-2]∙[IGFBP7] value is concerned, a rise of 0.1 (ng/ml) 2/1000 increased the risk of AKI of 2% (OR 1.21; 95% CI 1.07–1.36; p = 0.002) (Table 4). This evidence concerns the gene TIMP2 and acute kidney injury.