To study different functional classes of genes we used publicly available gene databases describing different gene classes – The Human Protein Atlas (housekeeping genes); Tumor-Associated Gene database (TAG database) (oncogenes); TSGene (tumor suppressor genes); CTDatabase (cancer/testis (CT) antigen genes); HomeoDB (HomeoBox genes); DeathBase (apoptosis genes); GeneOntology (differentiation genes); Biomedical Center Database (BMC GSTSE protein-coding genes and BMC GSTSE non-coding sequences). This evidence concerns the gene LBX1 and cancer.