11 key regulators (RPL11, RPL15, RPL19, RPL23A, RPL3, RPL5, RPL6, RPLP0, RPS11, RPS8 and RPSA) belong to the family of ribosomal proteins (RPs) which are involved in ribosomal biosynthesis and other eight predicted regulators (HSPA5, NOP2, RANBP2, SNU13, CUL7, CCT4, ASHA1 and EIF3A) have important functions reported to be associated with various other cancers. The gene discussed is CUL7; the disease is cancer.