Hypomethylation at cg18181703 (suppressor of cytokine signaling 3, SOCS3), cg06126421 (tubulin beta, TUBB), and cg05575921 (aryl hydrocarbon receptor repressor, AHRR) was associated with higher CRP levels and increased risk of future CHD [108]. The gene discussed is SOCS3; the disease is coronary artery disorder.