To explore whether RDW and PLT were independent prognostic factors of DLBCL patients, we performed a multivariate analysis, including age, advanced Ann Arbor stage, ECOG PS, LDH, extranodal sites, B symptoms, IPI score, bone marrow involvement, lower Hb level, RDW and PLT. The gene discussed is GSTM1; the disease is diffuse large B-cell lymphoma.