There is increasing evidence for expression of GnRH receptors on hormone‐dependent cancer cells where they can exert antiproliferative and/or proapoptotic effects and mediate effects of cytotoxins conjugated to GnRH analogues [http://www.ncbi.nlm.nih.gov/pubmed/15561800?dopt=AbstractPlus, http://www.ncbi.nlm.nih.gov/pubmed/15613448?dopt=AbstractPlus, http://www.ncbi.nlm.nih.gov/pubmed/14726258?dopt=AbstractPlus, http://www.ncbi.nlm.nih.gov/pubmed/15350601?dopt=AbstractPlus]. This evidence concerns the gene GNRHR and cancer.