In rodents, a sponateous gain‐of‐function matation of the TRPV3 gene causes the development of skin lesions with pruritus and dermatitis [http://www.ncbi.nlm.nih.gov/pubmed/16858425?dopt=AbstractPlus, http://www.ncbi.nlm.nih.gov/pubmed/22405088?dopt=AbstractPlus]. This evidence concerns the gene TRPV3 and skin disorder.