TNF and neoplasm: Immunostaining analysis of ECM proteins in TNFα‐CSG‐treated RIP1‐Tag5 tumours showed significantly reduced levels of laminin, nidogen‐1 and collagen IV (Fig 4A and B), whereas treatment with the CSG peptide, or with the blood vessel‐targeted TNFα‐RGR, (Johansson et al, 2012) had no effect (Fig 4A and B).