Therefore, we used HeLa cells because the cell line harbors wild‐type KRAS, BRAF, and PIK3CA genes.35, 55, 56 Similar to HT29 cells, treatment with Ab3‐8 did not affect tumor growth of HeLa cells, although we found that the expression of ASCT2 proteins in HT29 and HeLa cells was higher than that in SW1116 and HCT116 cells. Here, PIK3CA is linked to neoplasm.