Notably, upregulation of expression of MCM10 (Li et al, 2016), or repression of urothelial differentiation programs such as the BMP (Shin et al, 2014) and GATA (Choi et al, 2014) pathways, is associated with tumor progression and poor prognosis of BCs, suggesting that the functional downstream programs of the CDK1‐TFCP2L1 pathway might be similar in embryonic and tumor tissues. The gene discussed is MCM10; the disease is neoplasm.