Consistently, stable transfection of circ‐CUX1 or sh‐circ‐CUX1 #1 into IMR32 cells resulted in a significant increase or decrease in growth, tumor weight, Ki‐67 proliferation index, CD31‐positive microvessels, glucose uptake, lactate production, and ATP levels of subcutaneous xenograft tumors in nude mice (Fig 3C–E). Here, CUX1 is linked to neoplasm.