To determine further whether CBX7 overexpression was created in cells, we measured the downstream targets of CBX7, E-cadherin, and p65.10, 11 We found that overexpression of CBX7 increased the expression of E-cadherin but decreased the level of p65 in cervical cancer cells (Figures 1B and 1C). The gene discussed is CDH1; the disease is cervical cancer.