STAT3 and cardiomyopathy: - STAT3 overexpression in the heart protects against Dox-induced cardiomyopathy, probably through regulating expression of anti-oxidative MT1 and MT2- S-propargyl-cysteine (SPRC) possesses cardioprotective efficacy against Dox by stimulating STAT3 activation via gp130-mediated signaling in vitro and in vivo