Interestingly, the RARG-CPSF6 fusion was identified in a 26-years-old patient (no. 7, Table 1) with AML resembling APL, with a profoundly rearranged region on chromosome 12, where both RARG and CPSF6 are mapped, featuring breakpoints in these two genes and in the eukaryotic translation initiation factor 4B (EIF4B). This evidence concerns the gene EIF4B and acute myeloid leukemia.