CD163 and Zika virus infectious disease: The susceptibility of trophoblastic cells to ZIKV infection is still uncertain, with reports indicating either permissive or resistance towards ZIKV infection.9, 26, 27 Interestingly, the localisation of the ZIKV NS3 antigen to CD163+ Hofbauer cells did not agree with the positive detection of ZIKV RNA load in the placental tissue.