MCM2 and ovarian cancer: High expression of MCM2 level in malignant tumors, including ovarian cancer, is associated with several clinicopathological parameters such as advanced tumor grade, advanced stage, and poor prognosis (Davies et al., 2002; Going et al., 2002; Dudderidge et al., 2005; Majid et al., 2010; Abe et al., 2015).